| LEUCINE Leucine is an essential amino acid and one of the branched chain amino acids (the others are isoleucine and valine). These work together to protect muscle and act as fuel. They promote the healing of bones, skin, and muscle tissue, and are recommended for those recovering from surgery. Leucine also lowers elevated blood sugar levels and aids in increasing growth hormone production. Main Functions: • During times of starvation, stress, infection, or recovery from trauma, the body mobilizes leucine as a source for gluconeogenesis (the synthesis of blood sugar in the liver) to aid in the healing process. • It may have beneficial therapeutic effects on the prevention of protein wasting, as it occurs during starvation, semi-starvation, trauma, or recovery after surgery. • Insulin deficiency is known to result in poor utilization of leucine; therefore, individuals who suffer from glucose intolerance may require higher levels of leucine intake. • It may prevent muscle protein breakdown and stimulating muscle protein synthesis. • Potent stimulator of insulin. • Helps with bone healing. • Helps promote skin healing. • Modulates release of Enkephalins, which are natural pain-reducers. Leucine Deficiency: • Hyperinsulinemia • Depression • Chronic Fatigue Syndrome (Note: Deficiencies in BCAA in CFS, GWS, FM are associated with muscle weakness, fatigue, and post-exertional exhaustion). • Acute hunger • Kwashiorkor (starvation) • Vitamin B-12 deficiency in pernicious anemia Leucine Excess Seen In: Ketosis Rich Food Sources of Leucine Natural sources of leucine include brown rice, beans, meat, nuts, soyabeans, and whole wheat. |